President Medvedev threw down the nuclear gauntlet on the eve of President Obama’s landmark visit to Moscow today, challenging him to roll back a planned missile shield in Eastern Europe in return for making huge cuts in Russia’s nuclear arsenal.

The challenge came as the two prepared for historic talks on nuclear arms reduction with both already pledging major and reciprocal cuts.

Mr Medvedev raised the stakes in an interview with Italian media in which he insisted that any agreement would have to include concessions on the European-based missile shield proposed by President Bush.

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